Interleukin-11 drives early lung inflammation during Mycobacterium tuberculosis infection in genetically susceptible mice.
IL-11 is multifunctional cytokine whose physiological role in the lungs during pulmonary tuberculosis (TB) is poorly understood.Here, using in vivo administration of specific antibodies against IL-11, we demonstrate for the first time that blocking IL-11 diminishes histopathology and neutrophilic infiltration Shoes of the lung tissue in TB-infected